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KMID : 0358419690120010011
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Korean Journal of Obstetrics and Gynecology
1969 Volume.12 No. 1 p.11 ~ p.16
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Effect of Serum on fiver Tryptophan Pyrrolase Activity
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Abstract
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Tryptophan pyrrolase activity of rat liver was markedly inhibited by serum in vitro, and its --inhibition was reversed by hematin.
This inhibition by serum was due to the hematin-binding capacity of serum proteins, especially the serum albumin. Catalase and non-protein substances ubstances in the serum were. not involved
in the inhibition process.
Inhibition of tryptop an pyrrolase activity by serum could not be prevented by the substrate, tryptophan in vitro.
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